E-ISSN 2231-3206 | ISSN 2320-4672

2019, Vol:9,Issue:7

Research Articles
  • Natl J Physiol Pharm Pharmacol.2019; Volume:9(7):617-620 doi : 10.5455/njppp.2019.9.0309020042019
  • Assessment of serum lipid profile and electrolyte levels in Type II diabetes mellitus – A comparative study based on glycosylated hemoglobin levels
  • Nabeel Beeran Abdul Rahiman , Shobith Bangera , Sajla Shahul Hameed

Abstract

Background: There are currently around 40.9 million patients with diabetes mellitus (DM) in India. Imbalanced lipid profiles and deranged electrolyte levels in the body are commonly seen in DM patients. Glycosylated hemoglobin (HbA1 c) refers to the glucose-derived products of normal hemoglobin (HbA). Aims and Objectives: The objectives of this study were as follows: (A) To assess serum electrolyte levels, serum lipid profile, fasting blood sugar (FBS), and HbA1 c levels in Type II diabetic subjects and (B) to find out the correlation of lipid profile and electrolyte levels with HbA1 c.
Materials and Methods: This retrospective study was conducted in Yenepoya Medical College Hospital, Mangalore. In minimal residual disease, files of patients with type II DM of the age group of 25–70 years were retrieved and were grouped into Group A (44 uncontrolled Type II diabetes patients with HbA1 c ≥6.5%) and Group B (44 controlled Type II diabetic subjects with HbA1 c < 0.001) of serum sodium, potassium, and HDL levels and a statistically significant increase (P < 0.001) of FBS, TC, triglyceride, and LDL levels in Group A (uncontrolled Type II diabetes) compared to Group B (controlled Type II diabetes). Conclusion: HbA1 c can be used as an effective indicator of dyslipidemia and electrolyte imbalance, and in this way, early diagnosis of dyslipidemia and electrolyte imbalances can be used to prevent complications in Type II DM patients.