Abstract
Background: Infertility is the most common problem in recent times. Primary infertility is the main concern in infertile couples. Different groups of pharmacological agents are available in the market to induce ovulation. Aims and Objectives: The purpose of this retrospective analysis of cost variation in ovulation inducing agents is to compare the cost-analysis of various ovulation induction agents which are used in infertility patients. Materials and Methods: To review the price list of ovulation induction agents, the current index of medical stores April 2018 and online sources were used as an information guide. Results: The cost of 11 drugs were analyzed, which were manufactured by different pharmaceutical companies in different doses and formulations in Indian market. Table 1 shows the variation in price of parenteral ovulation induction agents. The cost variation is higher in human menopausal gonadotropin 150 IU (206.76), cetrorelix 0.25 mg (190.43) followed by chorionic gonadotropin 2000 IU (181.25). Table 2 shows the variation in price of oral ovulation induction agents. The cost variation is more in Letrozole 2.5 mg (6566.66) followed by clomifene 50 mg (217.65). Conclusion: There are ample differences in the cost of different brands of ovulation inducing agents available in India. All agents have significant role in the management of infertility. The clinicians prescribing these drugs should have awareness of these cost variations, so as to reduce the cost of drug therapy and increase patient adherence to the therapy.