E-ISSN 2231-3206 | ISSN 2320-4672

2018, Vol:8,Issue:2

Short Communication
  • Natl J Physiol Pharm Pharmacol.2018; Volume:8(2):292-294 doi : 10.5455/njppp.2018.8.0728417082017
  • Lower significant rate of etomidate-induced myoclonus for procedural sedation in emergency department of a tertiary care hospital
  • Ashly Alexander Fernandez, Neethu C M

Abstract

Background: Etomidate drug is commonly used for procedural sedation in the emergency department (ED). The incidence rate of etomidate-induced myoclonus is 33%. Aims and Objectives: In this study, we aimed to contradict that etomidate- induced myoclonus is less significant than the reported incidence rate.
Materials and Methods: This prospective study was performed between June 2016 and November 2016 in the ED of Amrita Institute of Medical Sciences, a tertiary care hospital. In the ED, procedural sedation was carried out by the physician. Adult patients receiving etomidate were enrolled for the study.
Results: The presence of myoclonus was noticed, and its duration was reported using the myoclonus scale. A total of 166 (116 males and 50 females) patients enrolled in the ED for procedural sedation with etomidate were taken. The dose administered was 0.3 mg/kg. Myoclonus was observed in 4 (2.4%) of 166 sedations. The mean age was observed to be male and female. During procedural sedation, etomidate-induced myoclonus in ED was less significant than the reported values. Conclusion: From this, we came to the conclusion that the incidence to occur myoclonus with administration of etomidate is less when compare with other ED studies.