Abstract
                 Background: Clinical pharmacology (CP) promotes rational use of drugs by integrating pharmacological and medical  knowledge. Knowledge helps in enlightening others while attitude and practices define the health-related behavior.  Aims and Objectives: This study was done to assess the knowledge, attitude, and practice on setting up of CP department  among health-care professionals in a tertiary care hospital of South India. Materials and Methods: It was a questionnaire- based cross-sectional study carried out in the Department of Pharmacology of a Government Medical College in South  Kerala, India. A preformed structured questionnaire consisting of 30 questions (12 questions on knowledge, 9 on attitude,  and 9 on practices with appropriate scores) were distributed, filled and collected from pharmacology department and  analyzed. Descriptive analysis of data was done using Statistical Package for the Social Sciences 16. Results: Out of total  30 distributed questionnaires, all were completely filled (100% response rate) and considered for analysis. Participants had  good knowledge regarding CP with mean correct response 17.88 ± 3.8 (74.5%). Mean scores of attitude and practices related  questions were found to be 16.93 ± 1.25 (94.06%) and 14.03 ± 2.02 (77.9%), respectively. Conclusions: Participants had  an excellent positive attitude regarding setting up of a CP unit with good knowledge and practices. There is a compelling  need to set up CP department in Government Medical College, Thiruvananthapuram, which will pave ways to major  contribution in teaching, patient care, and research.