Abstract

Health-care providers mustbe cautious aboutthe adverse effectsof drugs, especially Stevens–Johnsonsyndrome, whichis a potentially fatal condition. Several drugs are at high risk of inducing Stevens–Johnson syndrome including allopurinol, sulfonamides, cephalosporins, quinolones, phenytoin, carbamazepine, and nonsteroidal anti-inflammatory drugs. Owing to high risk of mortality, management of patients requires rapid diagnosis, identification and discontinuation of the causative drug, and specialized support care.