Abstract

Background: At present, there are considerable scientific evidences to suggest that nutritive and non-nutritive plant-based dietary factors can inhibit the process of carcinogenesis effectively.Aimsand
Objective: The aimof the presentstudy was to useessentialoilsextractedbydifferentmethodsfrom Achillea fragrantissima(hexaneextract[HE]andoilextract[OE])inthe manufactureofsoap,whichcanbeusedasanti-inflammatoryagent.MaterialsandMethods:Theanti-inflammatoryeffectof volatile oilwas studiedusing carrageenaninducedpawedemamethod at100 mg/kgdoseorally. Furthermore, italso studies the chemical composition of Achillea extracts by GC-MS.
Results: This study demonstrated that extracts of Achillea fragrantissima have excellent anti-inflammatory properties. Of the two extracts analyzed by gas chromatography-mass spectrometry (GC-MS), there were differences in thechemical composition of essential oil oftwo extracts. Bisabolol, bisabolol oxide,menthol,andb-caryophyllenearethemajorconstituentsoftheAchilleaextract,somecompoundswerefoundinOEand not found in HE. Conclusion: Our observations supports Achillea fragrantissima which is used by many people in the northern region for medicinal uses, it is safe and it can be used as anti-inflammatory drug.