Abstract

Background: Esophageal manometry is mandatory for localization of lower esophageal sphincter (LES) in patients undergoing ambulatory esophageal pH-metry for proper positioning of the pH-sensing catheter. Manometry not only gives the location of LES but also provides its tone in terms of basal lower esophageal sphincter pressure (BLESP) in mm Hg. Aims and Objectives: To study the LES pressures in cases of gastroesophageal reflux disease and to evaluate its significance by determining correlation between LES pressures and DeMeester score.
Materials and Methods: In the study, 54 subjects with clinical diagnosis of gastroesophageal reflux participated. Manometry was performed using pneumohydraulic water perfused system, followed by a 24-h ambulatory esophageal pH-metry. The data were subjected to statistical analysis using SPSS software, ± ± version 22.
Results: The mean BLESP was 13.68 3.93 mm Hg, and DeMeester score was 16.94 9.57. A significant negative correlation with a Pearson’scorrelationcoefficient (r)of -0.632 (po 0.001) was seen between BLESP and DeMeester score. Conclusion: High DeMeester score as in cases of gastroesophageal reflux is found to be significantly negatively correlated with low values of BLESP.