Abstract

Background: Different studies suggest that Vitamin D3 has a role in regulation of insulin and its deficiency leads to the development of type 2 diabetes mellitus (DM). In a study by ICMR-INDIAB (NE), it was shown that the prevalence of type 2 DM is about 9% in Tripura. However, little is known regarding the blood level of Vitamin D3 among the rural ethnic population.Objectives: The objectives of this study were to assess the blood level of Vitamin D3 and its association with type 2 DM in rural ethnic population.
Materials and Methods: This cross-sectional study was undertaken from February 2018 to January 2019 at Multidisciplinary Research Unit of Agartala Government Medical College to assess the blood Vitamin D3 level in the rural ethnic population and its association with Type 2 DM. Two hundred and eight subjects were recruited from 10 different health camps. Blood samples were collected for detecting different blood glycemic parameters. The data were statistically analyzed using the Statistical Package for the Social Sciences. Pearson’s correlation coefficient was used to evaluate the association of blood Vitamin D3 with glycemic parameters.
Results: Of 208 ethnic subjects, 136 had insufficient while 72 had sufficient blood Vitamin D3 level. Overall, 65% prevalence of Vitamin D3 insufficiency has been observed in the study population. About 98.3% and 52.3% of insufficiency (<30 ng/ml) have been observed in diabetic and non-diabetic subjects, respectively.Conclusion: About 65% prevalence of Vitamin D3 insufficiency irrespective of diabetic status was found in this study. However, Vitamin D3 level and its inverse association with glycemic parameters in type 2 DM could not be established.