Abstract
Background: Hypothyroidism refers to a state that results in a deficiency of thyroid hormones, including hypothalamic or,pituitary disease and generalized tissue resistant to thyroid hormone. Thyroid-releasing hormone can cause a rise in serum,prolactin levels in patients of primary hypothyroidism. Objective: The objective of the study was to find the levels of serum,prolactin in patients who are having hypothyroidism and to observe the relationship of prolactin with thyroid-stimulating,hormone. Materials and Methods: A total of 150 patients coming to endocrinology clinic for thyroid-related problems,were selected for the study and analyzed for their serum T3, T4, thyroid-stimulating hormone (TSH), and prolactin levels,by enzyme-linked fluorescent assay technique using Vidas autoanalyzer from Biomeriuex, France. Results: Prolactin level,is high in the subclinical hypothyroid patients and hypothyroid patients as compared to euthyroid patients. Conclusion: In,our study, it was seen that the levels of prolactin rise in relation to rising TSH level in hypothyroid patients.