Abstract

Background: Human immunodeficiency virus (HIV) infection produces a panorama of mucocutaneous manifestations, which may be the presenting feature of the disease. Up to 90% individuals with HIV infection experience oral and or cutaneous complications during their illness. Objectives: Objectives of the study were to study the mucocutaneous manifestations profile of HIV-seropositive patients.
Materials and Methods: A total of 500 HIV-seropositive patients attending skin OPD during November 2012-September 2014, a 2 years study, were assessed for various mucocutaneous manifestations.
Results: Maximum number of patients 374 (74.80%) belonged to the age group (25-49 years) with males being more commonly affected M: F-1.6:1. Low socioeconomic class 477 (95.40%), illiterate 195 (39%), laborer 234 (46.80%), and married 468(93.60%) patients were the most commonly affected ones. Heterosexual 418 (83.60%) mode of transmission was the most common. Monogamic patients were maximum with 417 (83.40%) and 390 (78%) cases had seronegative partners. Among infections and infestation, the most common was dermatophytosis 132 (26.40%) followed by herpes simplex 53 (10.60%), multiple pyoderma in 46 (9.20%) cases, Scabies was seen in 15 (3%) patients with the most common oral lesion being candidiasis (35.71%). Pruritus was associated in 51 (10.20%) patients. CD4 count 3 was more than 200 cells/mm in 375 (75.00%) patients. Among total 14 patients with oral mucosal involvement, the most common was oral candidiasis in 5 (35.71%) patients. Of the total 25 patients with cutaneous drug reactions, morbilliform rash was the most common in 11 (44%) patients. Maximum number of cases 4 (44%) had nevirapine as the culprit drug. Conclusion: Mucocutaneous manifestations of HIV help in early identification of HIV cases. Better implementation of current strategies is needed to increase awareness and safe sexual behavior of the population.