Abstract

Background: Dengue viral infections are the most important mosquito-borne diseases of the Indian subcontinent and have become a major global public concern.
Objective: To evaluate hematological changes in serologically proven patients with clinical manifestations of dengue fever at tertiary care hospital.
Materials and Methods: Cases of fever, clinically suspected to be dengue were confirmed by immunochromatographic tests for dengue NS1 antigen and dengue IgM antibody during the period from September 2015 to November 2015. A total of 250 seropositive dengue cases were correlated with clinical features, hematological, and biochemical findings. Result: With the most common clinical feature—high grade fever (95%), the main hematological findings were raised hematocrit (>29%), leukopenia (44%), and thrombocytopenia (59%). Conclusion: Hemoconcentration, leukopenia, thrombocytopenia, raised SGPT, and raised serum bilirubin gave enough clues to test for dengue serology so as to reduce the morbidity and mortality because of this disease.