Abstract

Background: Serum zinc levels have been shown to fall after acute tissue injury, including myocardial infarction. Magnesium (Mg) is a cofactor in more than 300 enzyme systems in the human cells and it has a predominant role in the normal myocardial physiology.
Objective: Study was carried out to assess serum levels of zinc and Mg in patient with ischemic heart diseases (IHDs) (acute myocardial infarction [AMI] and angina pectoris).
Materials and Methods: Total 83 patients evaluated include 58 patients with AMI and 25 patients with angina pectoris. Serum zinc and serum Mg were estimated by atomic absorption spectroscopy method. Result: Serum zinc levels were higher in patients with AMI than in patients with angina on the 1st day (t = 8.44, P < 0.001) and on the 12th day (t = 6.42, P < 0.001) but on the 3rd day it was less in patients with AMI than in patients with angina (not significant). Serum Mg levels were significantly higher in patients with AMI than in patients with angina on the 1st day (t = 6.50, P < 0.001) and on the 12th day (t = 2.00, P < 0.001) but on the 3rd day they were significantly lower ( t = 12.77, P < 0.001). Conclusion: These results suggest that serum zinc and serum Mg have a modest association with the risk of IHDs and showing significant change during IHD.