E-ISSN 2231-3206 | ISSN 2320-4672

2016, Vol:5,Issue:7

Research Articles
  • Indi J Medic Science and P Health.2016; Volume:5(7):1447-1451 doi : 10.5455/ijmsph.2016.26082015230
  • A study on Transfusion Transmitted Infections (TTI), transfusion related complications and quality of life amongst the Beta-Thalassaemia major patients, in Jamnagar district
  • Neha A Patel, Sumit V Unadkat, Jitesh P Mehta, Sudha B Yadav

Abstract

Background: Thalassemia is considered the most common genetic disorder worldwide. The condition affects economical and psychosocial quality of life of whole family broadly. It is a serious public health issue throughout Indian subcontinent and southeast Asia.
Objective: (1) To study the prevalence of transfusion transmitted infections (TTIs) in patients of beta-thalassemia major who are on transfusion therapy, (2) to assess the complications of iron overload and complications owing to chelation therapy, and (3) to study psychosocial and economic burden on patients’ family.
Materials and Methods: This cross-sectional study was conducted in Thalassemia ward of Pediatric Department from December 2010 to December 2011. All the patients of beta thalassemia major on blood transfusion therapy were included in the study. Preformed, pretested questionnaire was used to interview the patients and their caretakers. Data entry and analysis were done using Microsoft Excel 2007 and SPSS software, version 17. Result: Prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) was 3.95%, 2.25%, and 2.25%, respectively. Six in every 10 patients ever have experienced from blood transfusion reactions. Almost 40% patients had left the studies owing to illness or they have not gone to school ever. Conclusion: Even after introduction of sensitive screening test, prevalence of TTIs is more in patients than general population. Quality of life is affected economically and psychosocially.