Abstract
                 Background: Self-medication can be described as a double-edged sword for its users, because it has both beneficial  and harmful effects. The practice of self-medication is influenced by various factors. Meghalaya being an antimalarial drug  resistant region is very much vulnerable to harms of self-medication. Objective: Therefore, this study was initiated to determine the prevalence of self-medication for allopathic drugs among  the rural population and to find out the association between certain socio-demographic characteristics and self-medication . Materials and Methods: The study was a community-based, cross-sectional study carried out at Sohiong area of  Mawphlang Block, East Khasi Hills district, Meghalaya, India. A total of 400 respondents of 18 years of age or more were  randomly selected for the study. Result: Prevalence of self-medication was found to be 55% for allopathic drugs. Higher percentages of self-medication  practices were seen among male gender (54.7%), people educated at least up to high school (64%), and in the younger  age group (55%). Mild illness (30%) was the most common reason for self-medication followed by unwillingness to go to  doctors (27%). Cough and common cold (28.3%) were found to be the most common symptoms for self-medication. Most  common source of information for self-medication was family members and friends (38.7%). Conclusion: Higher percentages of self-medication practices were seen among the males, higher educational and socio- economic status, and younger age group. Health education to people regarding responsible self-medication is necessary  to prevent misuse and adverse effect of self-medication.