Abstract
Giant cell tumor of tendon sheath is a benign soft tissue lesion most commonly found in the flexor aspect of the hand and wrist. Being uncommon in the foot and ankle, the unusual appearance of this lesion can at times imitate other lesions such as lipoma, synovial sarcoma, malignant fibrous histiocytoma, synovial cyst, and ganglion. Thus, it is vital to include this lesion in differential diagnoses, especially if the lesion is found to be anchored to any of the surrounding tendons. This article describes the unusual occurrence of giant cell tumor of the tendon sheath of extensor digitorum brevis of great toe anchored to the capsule of metatarsophalangeal joint, which is rarely described in the literature.