Abstract

Background: Increasing use of blood group distribution in the study of diseases has prompted us to use this technique in an attempt to assess the role of genetic factor in development of ischemic heart disease (IHD). Objectives: To see whether ABO blood group has an independent association with IHD besides other factors such as age, sex, religion, smoking, alcohol, occupation, hypertension, DM, and family history of myocardial infarction.
Materials and Methods: This study includes 410 subjects with history of chest pain. The presence of IHD is ruled out by Rose questionnaire followed by ECG and blood grouping.
Results: The incidence of IHD was three times more among blood group A and B subjects as compared to blood group O subjects. Conclusion: Significant association of ABO blood group and IHD is present.