Abstract

Background: The relationship between hypothyroidism and dyslipidemia is poorly understood.
Objective: We aimed to describe the relationship between serum thyroid-stimulating hormone (TSH) and fasting lipid profile.
Materials and Methods: This prospective study recruited 50 hypothyroid subjects with Hashimoto’s thyroiditis who attended the endocrinology clinic of a teaching hospital from August 2011 to October 2011.
Results: Serum TSH showed positive correlation with serum total cholesterol, triglyceride, and low-density lipoprotein cholesterol, but had negative correlation with high-density lipoprotein cholesterol (P > 0.05). Conclusion: Hypothyroidism leads to atherogenic lipid profile. However, our observation needs to be further validated by larger prospective studies.