Abstract
                 Background: Human immunodeficiency virus (HIV) is a major global public health problem. Health-care workers (HCWs)  are persons working in health-care setting. They are potentially exposed to infectious materials such as blood, tissue, and  specific body fluids and are very vulnerable to infections mediated by blood and blood products. Objective: The aim and objective of this study is to assess the awareness and practice toward post-exposure prophylaxis  (PEP) for HIV, which is an important strategy for prevention of HIV among HCWs. Material and Methods: A cross-sectional study was conducted from August 2014 to January 2015 among HCWs in   tertiary care hospital. Data were collected using pre-designed, semi-structured questionnaire from study participants. Data  were entered in MS Excel sheet and analyzed using SPSS v 16. Results are presented in frequencies and percentages. Results: About one-third (65.5%) of participants have heard of PEP for HIV. Ninety-nine (45%) respondents knew when  to initiate PEP for HIV. Approximately, one-fourth (23.2%) of the respondents knew the maximum acceptable delay to  take PEP for HIV and about half of the participants (52.7%) had knowledge regarding the duration of PEP to prevent HIV.  Among all HCWs, 47 (21.4%) were ever exposed to blood or body fluids or needle stick injury and out of these only 7  (14.9%) had taken PEP.  Conclusion: Awareness as well as practice of PEP for HIV among HCWs is inadequate. A training and regular sensitization   of all HCWs regarding PEP for HIV is recommended to improve their knowledge.