Abstract

ABSTRACT Background: Dengue infection is the most important one in terms of morbidity and mortality. If the illness is not identified early in the course and not treated promptly when indicated, case fatality rate of DHF can go over 20% and that of DSS can be as high as 44%. Aims &
Objective: To study the manifestations of seropositive dengue fever patients at tertiary care hospital Perambalur. Also to assess indicators associated with poor prognosis (DHF and DSS) for early recognition of complications.
Materials and Methods: The present cross sectional study was conducted on 60 hospitalized adult patients during the period of one year. All Patients were assessed for clinical presentation and closely observed with investigations for the progression disease and complications. MAC capture ELISA for IgM, IgG capture ELISA and NS1 antigen by sandwich ELISA were used for investigation.
Results: In the present study out of total 60 patients, more number of DF patients i.e. 33 (55%) were found followed by 19 (31.67%) of DHF cases and 8 (13.33%) of DSS cases. There were 61% secondary infections in our study. The common symptoms in the present study were 60 (100%) fever in all patients followed by 48 (80%) headache. Conclusion: Dengue fever infection was found more in younger age groups. The factors significantly associated with poor prognosis group (DHF/DSS) were anorexia, altered mentation, conjunctival injections, anaemia with Hb <10mg%, haemoconcentration with haematocrit > 40, thrombocytopenia and deranged liver enzymes SGOT.