Abstract

Background: Safe blood is a critical component in improving health care and in preventing the spread of infectious diseases. But the quality and safety of blood transfusion is still a concern for health-care personnel’s. The infectious diseases for which blood donors are screened in the hospital include HIV, Hepatitis B and C and Syphilis. Aims &
Objective: To study seroprevalence of HIV, HBV, HCV and SYPHILIS in blood donors at Tertiary Hospital. Material and Methods: This was Secondary data analysis. Data was procured from Blood bank of the tertiary hospital. All the blood donors in the records over a period of three years were included in the analysis. A through search of records revealed that total 27,407 donors had been screened over the period of three years Samples were screened for HIV, HBsAg, HCV and Syphilis. All reactive samples were retested before being labelled as seropositive. Seroprevalence of HIV, HBsAg, HCV and Syphilis; comparative analysis of three years data using Chi square for linear trend analysis; comparison between prevalence rates among voluntary and replacement donors using Chi square test.
Results: Of the 27,407 donors, 13,168 (48%) were replacement and 14,239 (52%) voluntary Donors; 95.40% were male. Seroprevalence of major blood-borne pathogens (HIV, HBV, HCV and Syphilis) was 1.67%. Seropositivity of HIV, HBsAg, anti- HCV, and syphilis was 0.30%, 0.85%, 0.21% and 0.25%, respectively. There was statistically significant difference (p<0.001) in the seropositivity of various markers between voluntary and replacement donors. Conclusion: On comparing the data of three years, an increasing trend in seroprevalence of HIV, HBsAg, anti- HCV was observed.